eUTOPIA: solUTion for Omics data PreprocessIng and Analysis

Kuvaus

Abstract Background Application of microarrays in omics technologies enables quantification of many biomolecules simultaneously. It is widely applied to observe the positive or negative effect on biomolecule activity in perturbed versus the steady state by quantitative comparison. Community resources, such as Bioconductor and CRAN, host tools based on R language that have become standard for high-throughput analytics. However, application of these tools is technically challenging for generic users and require specific computational skills. There is a need for intuitive and easy-to-use platform to process omics data, visualize, and interpret results. Results We propose an integrated software solution, eUTOPIA, that implements a set of essential processing steps as a guided workflow presented to the user as an R Shiny application. Conclusions eUTOPIA allows researchers to perform preprocessing and analysis of microarray data via a simple and intuitive graphical interface while using state of the art methods.
Näytä enemmän

Julkaisuvuosi

2019

Aineiston tyyppi

Tekijät

Angela Serra - Tekijä

Dario Greco - Tekijä

Veer Singh Marwah - Tekijä

Tuntematon organisaatio

Giovanni Scala - Tekijä

Harri Alenius - Tekijä

Pia Anneli Sofia Kinaret - Tekijä

Vittorio Fortino - Tekijä

figshare - Julkaisija

Projekti

Muut tiedot

Tieteenalat

Lääketieteen bioteknologia

Kieli

englanti

Saatavuus

Avoin

Lisenssi

Creative Commons Nimeä 4.0 Kansainvälinen (CC BY 4.0)

Avainsanat

Medical biotechnology

Asiasanat

Ajallinen kattavuus

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Liittyvät aineistot