Biological constraints for parameter values of large-scale biologically plausible human Neuroscience models

Kuvaus

This dataset contains 1.) time constants of excitatory and inhibitory neocortical neurons, collated from the NeuroElectro database, 2.) spike thresholds of excitatory and inhibitory neurons, collated from the NeuroElectro database, and 3.) posterior distributions of parameters of large-scale biologically plausible models of human Neuroscience data, estimated using likelihood-free inference (LFI) methods to fit these models to Magnetoencephalography (MEG) resting-state data (N=75). We used pooled versions of the time constants and spike threshold values in this dataset along with other biological constraints, to set prior distributions of parameters of large-scale biologically plausible models of human Neuroscience data. We then used LFI methods to estimate posterior distributions of these parameters from MEG resting-state data (N=75) - we have also shared the posterior distributions in this dataset. Examples of parameters for which we have shared posterior distributions include strengths of connections within and between excitatory and inhibitory neuronal populations, time constants of excitatory and inhibitory neuronal populations, and firing thresholds of excitatory and inhibitory neuronal populations. These posterior distributions could be used by other research groups to set prior distributions of parameters of their biologically plausible models, in both experimental and modeling studies.
Näytä enemmän

Julkaisuvuosi

2023

Aineiston tyyppi

Tekijät

Department of Neuroscience and Biomedical Engineering

Anttoni Ojanperä - Muu tekijä

Benedetta Toselli - Muu tekijä

Felix Siebenhühner - Muu tekijä

Gabriele Arnulfo - Muu tekijä

Matias Palva Orcid -palvelun logo - Muu tekijä

Samuel Kaski Orcid -palvelun logo - Muu tekijä

Satu Palva - Muu tekijä

Nitin Williams - Tekijä

Mendeley Data - Julkaisija

Univ Manchester, Jodrell Bank Centre for Astrophysics, University of Manchester, Sch Phys & Astron, Jodrell Bank Ctr Astrophys - Muu tekijä

Projekti

Muut tiedot

Tieteenalat

Kieli

Saatavuus

Avoin

Lisenssi

Creative Commons Nimeä 4.0 Kansainvälinen (CC BY 4.0)

Avainsanat

Asiasanat

Ajallinen kattavuus

undefined

Liittyvät aineistot