Tutkimustoiminnan kuvaus

Finnish-German biochemist, high school diploma from Gymnasium An der Stenner (Iserlohn, Germany), undergraduate studies at the University of Hamburg, PhD from the University of Helsinki, Finland in 2003 with Kari Alitalo: discovery of the first growth factors for lymphatic vessels: VEGF-C and VEGF-D. Since 2020 associate professor at the Faculty of Pharmacy, University of Helsinki. Experience in three biotech startups with several patents and three drugs in clinical trials: OPT-302/sozinibercept (developer, phase III), VGX-100 and Lymfactin (co-developer, up to phase I and II, respectively). Currently working on novel and sustainable protein expression systems.

Affiliaatiot

University of Helsinki
Yksikkö
Translational Cancer Biology Program/Individual Drug Therapy Research Program
Lähde: ORCID
Nimike
Group leader 2013 - 2020

Yksikkö
Molecular/Cancer Biology Laboratory
Lähde: ORCID
Nimike
Postdoctoral Fellow 2003 - 2013

Yksikkö
Molecular/Cancer Biology Laboratory
Lähde: ORCID
Nimike
Graduate Student 1996 - 2002

Helsingin yliopisto
Yksikkö
Drug Research Program
Lähde: ORCID
Nimike
Associate Professor in Pharmaceutical Protein Drug Research 2020

Wihuri Research Institute
Lähde: ORCID
Nimike
Postdoctoral Fellow 2013 - 2013

Vegenics Ltd/Circadian Technologies via Licentia Oy (now Opthea)
Lähde: ORCID
Nimike
Contract Researcher 2007 - 2011

Lymphatix Oy (acquired by Ark Therapeutics)
Lähde: ORCID
Nimike
Researcher 2006 - 2007

Helsinki University Licencing Ltd./Licentia Ltd.
Lähde: ORCID
Nimike
Contract Researcher 1999 - 2005

Heinrich-Pette-Institut Leibniz-Institut fur Experimentelle Virologie
Yksikkö
Group Hans Will
Lähde: ORCID
Nimike
Research Assistant 1994 - 1995

Koulutus

Tutkinnot
PhD 1997 - 2002 / University of Helsinki
BSc/"Vordiplom" 1990 - 1994 / University of Hamburg
MSc 1994 - 1997 / University of Helsinki
Baccalaureate 1980 - 1989 / Gymnasium An der Stenner

Julkaisut (55)

The Relationship between the Secondary Vascular System and the Lymphatic Vascular System in Fish
2023

Bioactive VEGF-C from E. coli
2022

Expansion and collapse of VEGF diversity in major clades of the animal kingdom
2022

Hankkeet (1)

Development of a biotherapeutical to counter cancer “resistance” to presently used anti- angiogenic drugsSuomen Akatemia2013 - 2018

Aktiviteetit ja palkinnot (9)

reviewertieteellisen lehden arvioijana toimiminen2021
reviewertieteellisen lehden arvioijana toimiminen2019
reviewertieteellisen lehden arvioijana toimiminen2020
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